6048229331
Associate Professor

Office
Medical Sciences Block C- Room 118
Education
Queen’s University at Kingston, 1993, B.Sc.H., Life Sciences
University of Toronto , 1995, M.Sc., Physiology
University of Toronto , 1999, M.D.
University of British Columbia, 2001, CCFP
University of British Columbia, 2003, Fellowship in Sports Medicine
University of British Columbia, 2006, PhD , Exercise Physiology
CURRENT PROJECTS: Interaction between exercise intensity, pollution and the cardiorespiratory system (Fraser Basin Council, Health Canada) Physiologic and genetic contributions to Acute Mountain Sickness (Natural Science and Engineering Research Council) Pharmacogenomics of salbutamol as an ergogenic aid in elite cyclists (World Anti-Doping Agency) High Altitude Pulmonary Edema, Immersion Pulmonary Edema and Lung Water During Exercise (BC Sport Medicine Research Foundation and the Canadian Academy of Sport and Exercise Medicine)

Specialization

Exercise Science – sports medicine, exercise physiology, environmental illness

Research

Dr. Koehle’s research program combines exercise and environmental physiology from basic mechanistic research to more clinical field studies in remote environments. He is interested in examining the underlying mechanisms of environmental illnesses such as altitude, heat and decompression illness and developing strategies for their prevention.


Publications

MacInnis M, Rupert JL and Koehle MS. (In Press) Evaluation of the balance error scoring system (BESS) test in the diagnosis of acute mountain sickness at 4380 m, High Alt Med Biol.

Carter EA and Koehle MS (2011) Immersion Pulmonary Edema in Female Triathletes. Pulm Med 2011;2011:261404.

MacInnis, M, Wang P, Koehle MS and Rupert JL. (2011) The genetics of altitude tolerance: the evidence for inherited susceptibility to acute mountain sickness. Occupational and Environmental Medicine.

Koehle MS, Giles LV, Walsh ML & White MD. (2010) The effects of lower body positive and negative pressure on the hypoxic ventilatory decline. Respir Physiol Neurobiol. Jun 30;172(1-2):37-41.

Wang P, Ha AY, Kidd KK, Koehle MS & Rupert JL. (2010) A variant of the endothelial nitric oxide synthase gene (NOS3) associated with AMS susceptibility is less common in the Quechua, a high altitude Native population. High Alt Med Biol 11, 27-30.

Koehle MS, Guenette JA & Warburton DE. (2009). Oximetry, heart rate variability, and the diagnosis of mild-to-moderate acute mountain sickness. Eur J Emerg Med. 17(2):119-122.

Koehle MS, Giles LV, Curtis AN, Walsh ML & White MD. (2009). Performance of a compact end-tidal forcing system. Respir Physiol Neurobiol 167, 155-161.

Wang P, Koehle MS & Rupert JL. (2009). Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness. High Alt Med Biol 10, 261-267.

Koehle M, Sheel W, Milsom W & McKenzie D. (2008). The effect of two different intermittent hypoxia protocols on ventilatory responses to hypoxia and carbon dioxide at rest. Adv Exp Med Biol 605, 218-223.

Iverson GL, Kaarto ML & Koehle MS. (2008). Normative data for the balance error scoring system

Book Chapters

Koehle MS (2006) Physical Activity in the cold and at altitude In: Brukner P and Khan K, Clinical Sports Medicine 3rd Edition, McGraw Hill, Sydney, 900-911.