Robert Boushel
Hans-Christer Holmberg
Jose Calbet
Drs. Robert Boushel, Jose Calbet (Affiliate professor), Hans Christer Holmberg (Affiliate Professor), and colleagues have published a study investigating Angiotensin-Converting Enzyme 2 (ACE2) in skeletal muscle. ACE2 enzymes generate proteins that control blood pressure. The SARS-CoV-2 virus penetrates human cells by binding to ACE2 receptors, causing COVID-19 infections. The study found that muscle ACE2 protein expression is higher in those with more body fat and lower in individuals with high cardiorespiratory fitness and low body fat.
For the full paper: Click Here.
citation:
Perez-Valera M, Martinez-Canton M, Gallego-Selles A, Galván-Alvarez V, Gelabert-Rebato M, Morales-Alamo D, Santana A, Martin-Rodriguez S, Ponce-Gonzalez JG, Larsen S, Losa-Reyna J, Perez-Suarez I, Dorado C, Curtelin D, Gonzalez-Henriquez JJ, Boushel R, Hallen J, de Pablos Velasco P, Freixinet Guilart J, Holmberg HC, Helge JW, Martin-Rincon M, Calbet JAL. Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle. Scand J Med Sci Sports. 2021 Sep 22. doi: 10.1111/sms.14061. Epub ahead of print. PMID: 34551157.