The 2019 Saltin International Graduate Course in Exercise & Clinical Physiology

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This year the Saltin International Course in Exercise and Clinical Physiology will be held in Denmark. The theme of this year’s course is ‘Exercise as Medicine’. The course is being organized by Centre for Physical Activity Research (CFAS), Rigshospitalet and University of Copenhagen, Denmark, and dates have been set for September 23-26, 2019.

Location: Comwell Borupgaard, Snekkersten, Denmark
Dates: September 23 – 26, 2019

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A 4-day intensive advanced graduate-level course that brings together faculty and students from Danish and Canadian Universities focusing on topics in exercise and clinical physiology.

This annual, integrative research-based course covers basic and applied science topics on various physiological systems and extends to common clinical physiological applications. Thematic areas in physiology will range from subcellular signaling to organ function and systemic integration.

The international aspect of the course facilitates exchange of diverse topics, research perspectives, experimental approaches, research design, and national traditions. Faculty plenary lectures, student research presentations, and extensive seminar format are intended to maximize student-student and student-faculty interaction, enrich learning and inspire creativity in research. The International Course also aims to enhance academic and research networks between Danish and Canadian institutions to enrich graduate student learning, faculty interaction and exploration of future research initiatives that result in student mobility, development of new programs, projects, partnerships, student involvement, and likelihood of longevity of collaboration. The course will provide a platform for launching national and international research funding initiatives.

The course is structured to form a foundational component of graduate study credits at Canadian universities and for ECTS credits at Danish Universities. The course is open to graduate students from around the world and will rotate annually between Canada and Denmark.

International Perspective

Canada and Scandinavia have strong cultural and business links with Canada being one of the strongest growing export markets for Danish companies. The Canadian and Danish Trade Commissions have built extensive networks for knowledge exchange based on a shared value system with continuing commitment to fruitful collaboration on many global issues including industry, culture and the arctic.  Universities across Canada and Denmark are committed to the ideal of academic scholarship and to the development of an international perspective to broaden and enrich educational quality and expand research innovation. As part of university missions, students are encouraged to participate in international exchanges and internships, courses and field schools. These opportunities foster appreciation of other perspectives, cultures and exposure to new expertise as a part of excellence in university education. Equity, diversity and responsibility to society are values upon which the mission of Canadian and Danish Universities are founded.  International collaborations between Canada and Denmark have been active for close to a century and have developed intellectual depth and high rates of research discovery. Notably, a rich tradition of scientific collaboration exists in the fields of physiology and exercise.

After receiving the Nobel Prize in 1920 for his work on the function of capillaries, August Krogh took an interest in the work of Frederick Banting and Charles Best on the glucose lowering peptide insulin. On a trip to North America in 1922 August and his wife Marie who was diabetic, visited Banting’s lab at the University of Toronto. Krogh verified Banting’s findings on insulin and upon return to Denmark was instrumental in the nomination of Banting & Macleod for the Nobel Prize. Krogh obtained a license for the protocol for insulin purification and began production immediately upon his return to Copenhagen. Together with the Danish physician H. C. Hagedorn, Krogh then founded the Nordic Insulin Laboratory and the Nordisk Insulin Foundation which today constitute the company Novo Nordisk and the Novo Nordisk Foundation.

Continuing Krogh and Lindhard’s pioneering work in the physiology of exercise and establishment of the Copenhagen School, the Swedish physiologist Bengt Saltin conducted groundbreaking research in exercise physiology at the August Krogh Institute, beginning with seminal work on oxygen uptake, exercise and muscle glycogen, and the role of the circulation in exercise training and performance. Amongst many accomplishments, Saltin was awarded the August Krogh Prize, The Novo Nordisk Prize and the International Olympic Prize. As Director of The Copenhagen Muscle Research Centre he led the field internationally, and was a strong proponent of international collaboration. He was awarded 12 honorary doctorates -3 from Canadian universities stemming from rich history of research collaboration (>75 publications) with Canadian scientists. Bengt Saltin was an organizing member of the first International Graduate Courses held in 2010 and 2011, and owing to the positive review of these courses, he urged their continuation.

'There is no doubt that not only was it an exceptional learning opportunity but also the beginning of professional networks were formed. There were a number of discussions among the groups on concrete future studies.’ Bengt Saltin, 2011 Course, Quebec City

The Saltin International Graduate Course in Clinical and Exercise Physiology will extend the strong scientific lineage between Denmark and Canada. In the field of Exercise Physiology, the respective countries rank in the top tier internationally for scientific impact per capita. In the previous courses held in Canada and Denmark faculty and students from 20 universities were represented. The experience for both faculty and students was unique and highly valued by faculty and students alike.

‘I have taken part in these courses and the experience was amazing. It is a great learning opportunity and you get to interact with world experts both formally and informally. You can meet fellow students from across Canada and Europe - in some cases developing friends for decades. I encourage you to strongly consider fitting this into your studies. You will not get many of these chances.’ Terry Graham- Professor Emeritus, 2011 Course, Quebec City

Program Committee

Name Title Department/School Institution
Ylva Hellsten Professor Department of Exercise and Sport Sciences University of Copenhagen
Niels Ørtenblad Professor Department of Sports Science and Clinical Biomechanics University of Southern Denmark
Clara Prats Associate Professor Department of Biomedical Sciences University of Copenhagen
Abigail Mackey Associate Professor Department of Biomedical Sciences University of Copenhagen
Bente Klarlund Pedersen Professor Centre for Physical Activity Research, Rigshospitalet University of Copenhagen

Organizing Committee

Name Title Department/School Institution
Bente Klarlund Pedersen Professor Centre for Physical Activity Research, Rigshospitalet University of Copenhagen
Inge Holm Head of Section Centre for Physical Activity Research, Rigshospitalet University of Copenhagen
Emil Toft Course Secretary Centre for Physical Activity Research, Rigshospitalet University of Copenhagen

 Course Objectives

  • To provide an innovative learning experience for graduate students through exposure to and interaction with an extensive group of internationally recognized scholars and student peers across Canada and Internationally.
  • To gain exposure to diverse research perspectives and experimental approaches to enrich student learning through plenary lectures by numerous renowned researchers and educators.
  • To facilitate interactive discussion on cutting edge topics, explore approaches to stimulate creativity and novelty in research design and enhance research study impact.
  • To gain experience in formulating and communicating research proposals.
  • To foster the formation of research networks between scientists and institutions for exploration of future academic research initiatives.
    • To participate in discussions on career paths and trajectory.
  • To gain experience presenting research to peers and scholars.

Course Outcomes

Graduate students will have the unique opportunity to interact closely with scholars in their field over a 4-day period. Students will be exposed to state-of-the-art experimental approaches that may be implemented in their own research to enhance sophistication and novelty. Valuable experience will be gained through oral presentation of their own research in an international setting and collegial atmosphere. The opportunity exists to develop collaborative relationships, formal partnerships with peers and faculty at national and international levels, and discuss funding avenues. Students will gain insight on teaching approaches and responsibilities in the academic setting.

Course Credits

Students may register for a 3-credit graduate seminar course at their home institution, or a KIN 500 course at UBC. Students are expected to give a poster presentation at the course. For further information contact the Graduate Program Director at saltincourse.kin@ubc.ca.

Venue

Comwell Borupgaard is situated in the town of Snekkersten located on the east coast of Denmark, 40 km north of Copenhagen. The venue is easily (directly) accessible by train from the airport.

Comwell Borupgaard
Nørrevej 80, 3070 Snekkersten
Denmark

Fees

Costs: $1200 CAD, covers 4-night double occupancy and all meals. There is no course registration fee.

Students are expected to arrange and cover their own travel.

Students will be notified of acceptance to the course after registration.

 jump to > Day 2 | Day 3 | Day 4

Saltin International Graduate Course in Exercise and Clinical Physiology Program

Day 1

9:00-9:30 Registration and Coffee
9:30-9:45 Welcome and Introduction
Bente Karlund Pedersen
Session#1: Exercise as Medicine - the Methods
Chair: Ylva Hellsten
9:45-10:05 Exercise as medicine - measurement of physical activity and fitness
Paolo Caserotti
10:05-10:25 Physiological methods in exercise as medicine
Carsten Lundby 
10:25-10:45 Molecular methods in exercise as medicine
Robert Boushel
10:45-11:05 Animal models in exercise as medicine
Henriette Pilegaard
11:05-11:15 Short Break
11:15-12:15 Workshop on how to design a translational study
Facilitators: 
Clara Prats and Abigail Mackey
12:15-13:00 Lunch
Session#2: Exercise, Muscle and Tendons
Chair: Robert Boushel
13:00-13:30 Muscle lipid droplet and glycogen metabolism in exercise, training and disease
Abigail Mackey
13:30-14:00 Targeting Exercise Activated Pathways to Counter Side Effects of Antipsychotic Drugs
Niels Ørtenblad
14:00-14:30 Discussion 
14:30-17:00 Recreation Break
17:00-19:00 Workshop on research dissemination and pitching
Facilitators: Rudi Westendorp and  Morten Zacho
19:00-20:30 Dinner, Networking and Science Games

Day 2

Session#3: Exercise and Diabetes
Clara Prats
8:00-8:30 Models and basic mechanisms
Jørgen Wojtaszewski
8:30-9:00 Exercise as means to counter hyperglycemia
David Wright
9:00-9:30 Clinical intervention studies
Mathias Ried-Larsen
9:30-10:00 Discussion
10:00-10:30 Break
Session#4: Exercise and the Cardiopulmonary System
Chair: Niels Ørtenblad
10:30-11:00 How to train a patient with cardiovascular disease
Michael J. Joyner
11:00-11:30 Humans in hypoxia: A conspiracy of maladaptation?
Jerry A. Dempsey
11:30-12:00 The impact of exercise training on vascular function in hypertension
Ylva Hellsten
12:00-12:30 Discussion
12:30-13:15 Lunch
13:15-14:00 Workshop on how to design a translational study (Continued)
Facilitators: Clara Prats and Abigail Mackey
Session#5: Exercise and Aging
Chair: Terry Graham
14:00-14:30 (TBD)
Gianni Parise
14:30-15:00 Strength and power training for the oldest old: can we reverse the functional clock
Paolo Caserotti
15:00-18:30 Recreation Break - Optional outing to e.g. Louisiana Museum of Modern Art
18:30-19:30 Poster Pitching
19:30-20:30 Dinner

Day 3

Session#6: Exercise and Obesity
Chair: David Wright
8:00-8:30 TBA
Mary-Ellen Harper
8:30-9:00 Skeletal muscle metabolism during exercise and obesity
Clara Prats
9:00-9:30 Exercise and postprandial metabolism
Terry Graham
9:30-10:00 Discussion
10:00-10:30 Break
10:30-11:00 Session#7: Exercise and Neurology
Chairs: Abigail Mackey
10:30-11:00 Exercise and multiple sclerosis
Ulrik Dalgas
11:00-11:30 Exercise and dementia
Steen Hasselbalch (tbc)
11:30-12:00 Discussion
12:00-13:00 Lunch

Session#8: Exercise and Cancer
Chair: Pernille Højman
13:00-13:30 A translational perspective on exercise and cancer
Jesper F. Christensen (tbc)
13:30-14:00 Barriers and motivation in exercise and cancer
Julie Midtgaard (tbc)
14:00-14:30 Discussion
14:30-16:00 Group presentations of how to design a translational study
Facilitators: Clara Prats and Abigail Mackey
16:00-16:30 Course Evaluation
16:30-18:00 Recreational Break
18:00-19:00 Poster Pitching
19:00-20:45 Dinner and Dinner Talks by Jerry, Terry, and Mike
20:45-21:00 Poster and Study Design Prize Award Ceremony

Day 4

International Symposium on "Exercise as Medicine in a Mechanistic Perspective" 

9:00-9:30 Registration and Coffee
9:30-9:35 Welcome 
Bente Klarlund Pedersen, Centre of Inflammation & Metabolism, Rigshospitalet, Copenhagen
9:35-10:15 Key-note lecture on: Exercise as Medicine (TBD)
Michael J. Joyer
10:15-10:45 Exercise, Muscle and Tendons (TBD)
Michael Kjær
10:45-11:15 Coffee
11:15-11:45 Exercise and Insulin Sensitivity
Erik A. Richter
11:45-12:15 Exercise and the Cardiopulmonary System (TBD)
Ylva Hellsten
12:15-14:00 Lunch and Poster Pitching
14:00-14:30 Exercise and Aging (TBD)
TBA
14:30-15:00 Exercise and Obesity (TBD)
Mary-Ellen Harper
15:00-15:30 Coffee
15:30-16:00 Exercise and Neurology (TBD)
TBA
16:00-16:30 Exercise and Cancer (TBD)
Pernille Højman
16:30-16:45 PhD Course and Symposium closing
Bente Klarlund Pedersen

* Lectures tailored to student learning: 25 min+5 min Q/A
* 40 student registrants
* Canadian (3 cr) and European (3.5ECTS) Course credit

  • Assoc. Prof. Abigail Mackey, Dept. of Biomedical Sciences, University of Copenhagen, Denmark
  • Prof. Bente Klarlund Pedersen, Centre for Physical Activity Research, Rigshospitalet and University of Copenhagen, Denmark
  • Prof. Carsten Lundby, Inland Norway University of Applied Sciences, Lillehammer, Norway and Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark
  • Assoc. Prof. Clara Prats, Dept. of Biomedical Sciences, University of Copenhagen, Denmark and Assoc.
  • Prof. David Wright, Human Health and Nutritional Sciences, University of Guelph, Canada
  • Prof. Erik A. Richter, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark
  • Prof. Gianni Parise, McMaster University, Canada
  • Prof. Henriette Pilegaard, Cell Biology and Physiology, University of Copenhagen, Denmark
  • Prof. Jerry A. Dempsey, Dept. of Population Health Sciences, University of Wisconsin, Madison, USA
  • Postdoc Jesper F. Christensen, PhD, Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark
  • Assoc. Prof. Julie Midtgaard, University Hospitals Centre for Health Research, Rigshospitalet and University of Copenhagen, Denmark
  • Prof. Jørgen Wojtaszewski, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark
  • Prof. Mary-Ellen Harper, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Canada
  • Group Leader Mathias Ried-Larsen, PhD., Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark
  • Prof. Michael J. Joyner, Mayo Clinic, Rochester, USA
  • Prof. Michael Kjær, Institute of Sports Medicine Copenhagen, Bispebjerg Hospital and University of Copenhagen, Denmark
  • Teach. Assoc. Prof. Morten Zacho, University of Southern Denmark, Odense, Denmark
  • Prof. Niels Ørtenblad, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
  • Assoc. Prof. Paolo Caserotti, Dept. of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
  • Group Leader Pernille Højman, Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark
  • Prof. Robert Boushel, School of Kinesiology, University of British Columbia, Vancouver, Canada
  • Prof. Rudi Westendorp, Section of Epidemiology, University of Copenhagen, Denmark
  • Prof. Steen Hasselbalch, Danish Dementia Research Centre, Rigshospitalet and University of Copenhagen, Denmark
  • Prof. Terry Graham, Human Health and Nutritional Sciences, University of Guelph, Canada
  • Assoc. Prof. Ulrik Dalgas, Department of Public Health - Sport Science, Aarhus University, Denmark
  • Prof. Ylva Hellsten, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark

2019 Saltin International Graduate Course Registration Form

 

Dr. Robert Boushel, Director
School of Kinesiology
War Memorial Gymnasium 210D
6081 University Boulevard
Vancouver, BC V6T 1Z1