Study title:
Investigating Age-Related Differences in Skeletal Muscle Extracellular Matrix Breakdown Following Acute Resistance Exercise
Principle Investigator:
Dr. Cameron Mitchell
Details:
The purpose of this study is to investigate age-related differences in how skeletal muscle responds to resistance exercise. In particular, we hypothesize that reduced collagen breakdown in the muscle plays a key role in age-related declines in muscle function. To measure these differences, we will take muscle biopsies and blood draws. You will also participate in fitness tests and a resistance exercise training session.
Eligibility:
Inclusion Criteria:
- Able to understand and communicate in English
- Between 19-30 or 65-85 years of age
Exclusion Criteria:
- BMI greater than 30
- Currently smoking cigarettes
- Any medical condition impacting the ability to participate in maximal exercise
- Type one or type two diabetes
- Diagnosis of cancer or have undergone cancer treatment in the past 12 months
- Taking blood-thinning medication or the presence of a bleeding disorder
- Lower body resistance or aerobic training in the previous 6 months (structured, moderate to vigorous)
- Resting blood pressure greater than 160/90 mmHg
- Taking any drug that alters skeletal muscle metabolism (i.e., Metformin, Benzodiazepines)
- Have taken fish oil, omega-3, serratiopeptidase, curcumin or collagen supplements in the last 3 months
- Allergy or unwillingness to consume gluten, soy or jam products
Poster:
Contact Information:
Please contact the Study Coordinator, Ally Schweitzer (allyson.schweitzer@ubc.ca) for more information.
Posting Expiration Date:
June 2023